Our CB4™ brand of medical cannabis products are based on science and engineered to deliver results.

CB4 Relief 0.5% Deep Rub Gel

Muscle & Joint Topical CBD – Deep Penetration Formula


CBD 250 mg/bottle
THC 9.5 mg/bottle

Opticann’s CB4 Relief Deep Rub Gel is a revolutionary cannabis topical formulated with a proprietary, scientifically tested, and proven enhanced permeation formulation that penetrates the skin for optimal results and quick absorption.

Each 50ml bottle delivers 250mg Cannabidiol (CBD 0.5% in concentration), balanced with the terpene Beta-Caryophyllene (BCP), and menthol—for a calm, cooling effect—proven to deliver CBD where it matters.

Data on topical CBD for pain relief exists in scientific literature. Well-engineered medical cannabis products should deliver CBD through the skin to be effective.

Scientific Evidence:

CBD Evidence for Pain and Inflammation
CBD Evidence for Localized Pain and Inflammation
CB4 Relief Evidence for Enhanced Dermal Absorption

Size Price
50 mL $39.99

To order, login to the Patient Portal or call Patient Care: 1-855-437-2266 to place an order over the phone.

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Clinical Data and Absorption Graph

CB4 Relief Deep Rub Gel is formulated with an advanced dermal penetration pharmaceutical formulation and is tested to show up to 6.5x more absorption through the dermal membranes than other topical products.

CBD Transmembrane Absorption Graph - CB4 Relief Topical vs. Standard CBD cream


Aqua, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Isohexadecane, Polysorbate SD, Isopropyl Myristate, Polysorbate 80, Ethoxydiglycol, Menthol, Cannabis Extract, Eugenia Caryophyllus (Clove) Leaf Oil, Phenoxyethanol, Citric Acid.

The product image and label are provided for illustrative purposes only. Actual labels may vary.

Potency per 50 mL bottle:
250 mg CBD

How to Use

Directions: Patients should apply the vanishing gel to affected areas and sore spots by massaging into the skin until fully absorbed.

CB4 Relief Deep Rub Gel is fast acting and the higher absorption can lead to longer duration of effects of up to 8-12 hours.

FOR TOPICAL USE ONLY, NOT TO BE USED ON BROKEN SKIN OR NEAR THE EYES and caution should be used in patients with hypersensitivity to topical CBD.